Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 14/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 13/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.34 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583716 | 0.83 | P2RX7 (0.47) | P2RX7NR1H2NR1H3LMNA | |
| SCHEMBL7581592 | 0.71 | P2RX7 (0.39) | P2RX7NR1H2NR1H3 | |
| SCHEMBL7585196 | 0.71 | ALDH1A1 (0.48) | LMNA | |
| SCHEMBL7585721 | 0.71 | LMNA (0.38) | LMNA | |
| SCHEMBL7582668 | 0.67 | HTR2C (0.37) | — | |
| SCHEMBL27529415 | 0.67 | P2RX7 (0.49) | P2RX7NR1H2NR1H3LMNA | |
| SCHEMBL18913873 | 0.65 | P2RX7 (0.51) | P2RX7NR1H2NR1H3 | |
| SCHEMBL18913827 | 0.65 | P2RX7 (0.51) | P2RX7NR1H2NR1H3 | |
| SCHEMBL27450709 | 0.65 | P2RX7 (0.41) | P2RX7NR1H2NR1H3 | |
| SCHEMBL27489861 | 0.63 | P2RX7 (0.50) | P2RX7NR1H2NR1H3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | claimed |