Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583716 | 0.86 | P2RX7 (0.47) | LMNAHTTNPC1RAB9ATSHR | |
| SCHEMBL7590018 | 0.76 | DRD2 (0.41) | ALDH1A1USP2LMNAHTTL3MBTL1 | |
| Ethane SCHEMBL7590902 | 0.76 | ALDH1A1 (0.40) | ALDH1A1USP2LMNAHTTL3MBTL1 | |
| SCHEMBL7583803 | 0.74 | DRD2 (0.39) | ALDH1A1USP2LMNAHTTL3MBTL1 | |
| SCHEMBL7583792 | 0.73 | DRD2 (0.41) | ALDH1A1USP2LMNAHTTL3MBTL1 | |
| SCHEMBL18913827 | 0.73 | P2RX7 (0.51) | ALDH1A1RAB9AKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL18913873 | 0.73 | P2RX7 (0.51) | ALDH1A1RAB9AKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL7586749 | 0.71 | P2RX7 (0.44) | LMNA | |
| Ethane SCHEMBL7588368 | 0.71 | P2RX7 (0.46) | ALDH1A1USP2LMNAHTTL3MBTL1 | |
| Ethane SCHEMBL7586900 | 0.71 | P2RX7 (0.41) | ALDH1A1USP2LMNAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | claimed |