Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 5/20 | 0.42 |
| ▸ | BCR | P11274 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590779 | 0.84 | AKR1B1 (0.45) | SMN1; SMN2RAB9ANPC1MITFPKM | |
| SCHEMBL7589532 | 0.84 | NPC1 (0.50) | NPBWR1RAB9ANPC1MITFPKM | |
| SCHEMBL7587542 | 0.84 | NPC1 (0.56) | SMN1; SMN2RAB9ANPC1MITFPKM | |
| SCHEMBL7587363 | 0.82 | NPC1 (0.55) | SMN1; SMN2RAB9ANPC1MITFPKM | |
| SCHEMBL7588481 | 0.80 | NPC1 (0.47) | HTTSMN1; SMN2RAB9ANPC1MITF | |
| SCHEMBL7586423 | 0.80 | NPC1 (0.55) | SMN1; SMN2RAB9ANPC1MITFPKM | |
| SCHEMBL12604468 | 0.79 | NPC1 (0.51) | NPBWR1HTTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7587105 | 0.78 | MAPT (0.48) | SMN1; SMN2RAB9ANPC1MITFPKM | |
| SCHEMBL7761997 | 0.76 | ALOX5 (0.43) | HTTRAB9ANPC1MITFPKM | |
| SCHEMBL9229803 | 0.75 | NPC1 (0.62) | NPBWR1SMN1; SMN2RAB9ANPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1231982-A2 | USE OF PHTHALAZINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001082877-A2 | USE OF PARP INHIBITORS IN COSMETIC PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |
| WO-2000067734-A2 | USE OF PHTHALAZINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |