Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587363 | 0.84 | NPC1 (0.55) | NPC1MITFPKMRAB9AMAPT | |
| SCHEMBL7586423 | 0.82 | NPC1 (0.55) | NPC1MITFPKMRAB9AMAPT | |
| SCHEMBL7588481 | 0.82 | NPC1 (0.47) | NPC1MITFPKMRAB9AMAPT | |
| SCHEMBL7587542 | 0.79 | NPC1 (0.56) | NPC1MITFPKMRAB9AKMT2A | |
| SCHEMBL7590779 | 0.79 | AKR1B1 (0.45) | NPC1MITFPKMRAB9AMAPT | |
| SCHEMBL7589532 | 0.79 | NPC1 (0.50) | NPC1MITFPKMRAB9AMAPT | |
| SCHEMBL30578356 | 0.79 | KMT2A (0.46) | NPC1RAB9AMAPTHTTKMT2A | |
| SCHEMBL7759225 | 0.78 | GAA (0.44) | NPC1MITFPKMRAB9AMAPT | |
| SCHEMBL7586791 | 0.76 | NPBWR1 (0.48) | NPC1MITFPKMRAB9AMAPT | |
| SCHEMBL28766387 | 0.74 | NPC1 (0.65) | NPC1RAB9AHTTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082877-A2 | USE OF PARP INHIBITORS IN COSMETIC PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |