Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.68 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.65 |
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773820 | 0.88 | CHRM1 (0.75) | CYP2D6CYP2C9OPRM1OPRL1OPRK1 | |
| SCHEMBL7963223 | 0.85 | CYP2D6 (0.77) | CYP2D6CYP2C9OPRM1OPRL1OPRK1 | |
| SCHEMBL6404540 | 0.85 | PLD1 (0.81) | CYP2D6CYP2C9OPRM1OPRL1OPRK1 | |
| SCHEMBL2982735 | 0.83 | CHRM1 (0.71) | CYP2D6CYP2C9OPRM1OPRL1OPRK1 | |
| SCHEMBL28539041 | 0.83 | CYP2D6 (0.86) | CYP2D6CYP2C9OPRM1OPRL1OPRK1 | |
| SCHEMBL5984495 | 0.83 | CYP2D6 (0.85) | CYP2D6CYP2C9OPRM1OPRL1OPRK1 | |
| SCHEMBL23374511 | 0.82 | PLD1 (0.72) | CYP2D6CYP2C9OPRM1OPRL1OPRK1 | |
| SCHEMBL6404859 | 0.82 | CHRM1 (0.88) | CYP2D6CYP2C9OPRM1OPRL1OPRK1 | |
| SCHEMBL5771940 | 0.82 | OPRM1 (0.88) | CYP2D6CYP2C9OPRM1OPRL1OPRK1 | |
| SCHEMBL7849321 | 0.81 | OPRM1 (1.00) | OPRM1OPRL1OPRK1DRD2PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100861-A1 | 1-(3-PHENYLOXYPROPYL)PIPERIDINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2002-12-19 | — | — | WO | disclosed |