Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.77 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.77 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.74 |
| ▸ | DRD2 | P14416 | 2/20 | 0.66 |
| ▸ | DRD4 | P21917 | 2/20 | 0.66 |
| ▸ | DRD3 | P35462 | 2/20 | 0.66 |
| ▸ | PLD2 | O14939 | 1/20 | 0.65 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.65 |
| ▸ | AKT1 | P31749 | 1/20 | 0.64 |
| ▸ | AKT2 | P31751 | 1/20 | 0.64 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665096 | 0.87 | OPRM1 (1.00) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL20763210 | 0.85 | OPRM1 (1.00) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL5774325 | 0.84 | OPRM1 (0.78) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL22605511 | 0.83 | OPRM1 (0.71) | OPRM1OPRK1OPRD1DRD2DRD4 | |
| SCHEMBL29518448 | 0.83 | OPRM1 (0.71) | OPRM1OPRK1OPRD1DRD2DRD4 | |
| SCHEMBL4446720 | 0.83 | PLD2 (0.72) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL8863557 | 0.83 | OPRM1 (0.91) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| Oxalic Acid SCHEMBL5778025 | 0.83 | OPRM1 (0.91) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL12375874 | 0.82 | OPRM1 (0.77) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL7068005 | 0.82 | OPRM1 (0.84) | OPRM1OPRK1OPRL1OPRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142587-A1 | REMEDIES FOR PAIN | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |