Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 14/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 13/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL7588368 | 0.87 | P2RX7 (0.46) | P2RX7NR1H2NR1H3TSHRCNR1 | |
| Ethane SCHEMBL7590902 | 0.85 | ALDH1A1 (0.40) | P2RX7NR1H2NR1H3TSHRCNR1 | |
| SCHEMBL27553152 | 0.79 | P2RX7 (0.44) | P2RX7NR1H2NR1H3TSHRNPSR1 | |
| SCHEMBL18913873 | 0.76 | P2RX7 (0.51) | P2RX7NR1H2NR1H3TSHRNPSR1 | |
| SCHEMBL18913827 | 0.76 | P2RX7 (0.51) | P2RX7NR1H2NR1H3TSHRNPSR1 | |
| SCHEMBL27529415 | 0.75 | P2RX7 (0.49) | P2RX7NR1H2NR1H3TSHRALDH1A1 | |
| SCHEMBL7590018 | 0.72 | DRD2 (0.41) | P2RX7ALDH1A1LMNAHTTUSP2 | |
| SCHEMBL7583716 | 0.72 | P2RX7 (0.47) | P2RX7NR1H2NR1H3TSHRNPSR1 | |
| SCHEMBL7585196 | 0.71 | ALDH1A1 (0.48) | TSHRNPSR1ALDH1A1LMNAHTT | |
| SCHEMBL7583792 | 0.70 | DRD2 (0.41) | P2RX7ALDH1A1LMNAHTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114596-C | Biphenyl derivatives | EISAI CO LTD (JP) | 2003-07-16 | — | — | CN | claimed |
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | claimed |
| CN-1114596-C | Biphenyl derivatives | EISAI CO LTD (JP) | 2003-07-16 | — | — | CN | disclosed |
| CN-1412661-A | Chinese character name code keyboard input method | LU YUSHAN (CN) | 2003-04-23 | — | — | CN | disclosed |
| CN-1290700-A | Phenyl piperazine derivatives | EISAI LTD (JP) | 2001-04-11 | — | — | CN | disclosed |