Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590974 | 0.83 | HSD17B1 (0.36) | ALDH1A1HSD17B1HSD17B2HTR7ESR2 | |
| Hydrochloric Acid SCHEMBL8011897 | 0.82 | OPRK1 (0.35) | ALDH1A1HSD17B1HSD17B2HTR7ESR2 | |
| SCHEMBL7605203 | 0.82 | MAPT (0.39) | MAPTALDH1A1NPC1LMNAHPGD | |
| SCHEMBL7588577 | 0.82 | HSD17B1 (0.35) | HSD17B1HSD17B2ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL8022870 | 0.81 | MAPT (0.38) | MAPTALDH1A1NPC1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL8014383 | 0.81 | HSD17B1 (0.34) | HSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL7584081 | 0.80 | HSD17B1 (0.40) | HSD17B1HSD17B2CYP1A2PIM1PIM2 | |
| Hydrochloric Acid SCHEMBL8017915 | 0.79 | HSD17B1 (0.39) | HSD17B1HSD17B2CYP1A2PIM1PIM2 | |
| SCHEMBL7591741 | 0.78 | MTNR1A (0.44) | MAPTALDH1A1LMNAKDM4EHSD17B1 | |
| SCHEMBL7588665 | 0.78 | ESR1 (0.40) | HSD17B1HSD17B2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864559-B1 | Substituted amino compounds and their use as analgesic active substances | GRUENENTHAL GMBH (DE) | 2002-06-05 | — | — | EP | disclosed |
| EP-0864559-A1 | Substituted amino compounds and their use as analgesic active substances | Grünenthal GmbH (DE) | 1998-09-16 | — | — | EP | disclosed |