Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | PLG | P00747 | 7/20 | 0.50 |
| ▸ | KLK1 | P06870 | 7/20 | 0.50 |
| ▸ | KLK6 | Q92876 | 7/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.46 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.46 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7604067 | 0.98 | HDAC6 (0.53) | HDAC6HDAC3NCOR2PLGKLK1 | |
| SCHEMBL8397578 | 0.86 | MPO (0.64) | HDAC6HDAC3NCOR2PLGKLK1 | |
| SCHEMBL28345255 | 0.82 | MPO (0.48) | HDAC6KLKB1MPOKDM4EGAA | |
| SCHEMBL8815944 | 0.79 | KLKB1 (0.71) | KLKB1KDM4EHIF1AEGFRCTSB | |
| SCHEMBL3846227 | 0.79 | KLKB1 (0.71) | KLKB1KDM4EHIF1AEGFRCTSB | |
| SCHEMBL21632307 | 0.78 | PLG (0.49) | PLGKLK1KLK6KLKB1KDM4E | |
| SCHEMBL852964 | 0.77 | CA12 (0.61) | PLGKLK1KLK6KLKB1KDM4E | |
| Hydrochloric Acid SCHEMBL1165499 | 0.76 | CA12 (0.59) | PLGKLK1KLK6KLKB1KDM4E | |
| SCHEMBL13293974 | 0.76 | PLG (0.61) | PLGKLK1KLK6KLKB1 | |
| SCHEMBL732923 | 0.76 | ALOX5 (0.64) | HDAC6KLKB1MPOKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920413-B1 | BORONIC COMPOUND COMPLEXING REAGENTS AND COMPLEXES | PROLINX INC (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-0915832-B1 | BORONIC COMPOUND COMPLEXING REAGENTS AND HIGHLY STABLE COMPLEXES | PROLINX INC (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-0920413-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND COMPLEXES | PROLINX, INC. (US) | 1999-06-09 | — | — | EP | disclosed |
| EP-0915832-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND HIGHLY STABLE COMPLEXES | PROLINX, INC. (US) | 1999-05-19 | — | — | EP | disclosed |
| US-5877297-A | Boronic compound complexing reagents and highly stable complexes | PROLINX, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5872224-A | Boronic compound complexing reagents and highly stable complexes | PROLINX, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5869623-A | Boronic compound complexing reagents and complexes | SYSTEMIX (US) | 1999-02-09 | — | — | US | disclosed |
| US-5859210-A | Boronic compound complexing reagents and complexes | PROLINX, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5847192-A | Boronic compound complexing reagents and complexes | PROLINX, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| US-5837878-A | Boronic compound complexing reagents and highly stable complexes | PROLINX, INC. (US) | 1998-11-17 | — | — | US | disclosed |
| US-5777148-A | Boronic compound complexing reagents and highly stable complexes | PROLINX, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5744627-A | Boronic compound complexing reagents and complexes | PROLINX, INC. (US) | 1998-04-28 | — | — | US | disclosed |
| WO-1998005627-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND HIGHLY STABLE COMPLEXES | PROLINX, INC. (US) | 1998-02-12 | — | — | WO | disclosed |
| WO-1998005629-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND COMPLEXES | PROLINX, INC. (US) | 1998-02-12 | — | — | WO | disclosed |