Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223718 | 0.86 | MAOB (0.50) | MAPTLMNAALDH1A1NPSR1MAOB | |
| SCHEMBL13707146 | 0.76 | MAPT (0.44) | MAPTLMNAALDH1A1NPSR1KMT2A | |
| SCHEMBL3380070 | 0.74 | MAOA (0.58) | MAPTALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL1740014 | 0.73 | TDP1 (0.38) | MAPTLMNAALDH1A1NPSR1KMT2A | |
| SCHEMBL9770101 | 0.73 | LMNA (0.50) | MAPTLMNAALDH1A1NPSR1ACHE | |
| SCHEMBL5645870 | 0.70 | MAOB (0.52) | ALDH1A1MAOBTSHRKDM4E | |
| SCHEMBL3851412 | 0.69 | MAPT (0.47) | MAPTLMNAALDH1A1NPSR1KMT2A | |
| SCHEMBL1987774 | 0.69 | MAOB (0.46) | MAPTLMNAALDH1A1NPSR1ACHE | |
| SCHEMBL17752846 | 0.69 | ACHE (0.53) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL1709979 | 0.68 | RAB9A (0.60) | MAPTLMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844269-B1 | BLOCK COPOLYMER HAVING FUNCTIONAL GROUPS AT BOTH ENDS | KATAOKA KAZUNORI (JP) | 2002-10-23 | — | — | EP | disclosed |
| US-5929177-A | LIVING POLYMER WITH HYDROPHILIC, HYDROPHOBIC SEGMENTS | Kataoka, Kazunori (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0844269-A1 | BLOCK POLYMER HAVING FUNCTIONAL GROUPS AT BOTH ENDS | Kataoka, Kazunori (JP) | 1998-05-27 | — | — | EP | disclosed |