SCHEMBL7587610

SCHEMBL7587610

c1ccc(-c2ccc(-c3ccc(-c4ccc(-c5ccccc5)s4)cc3)s2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 5/20 0.62
HSD17B2 P37059 5/20 0.62
NQO2 P16083 3/20 0.61
RAB9A P51151 2/20 0.58
MEN1 O00255 1/20 0.58
POLB P06746 1/20 0.58
KMT2A Q03164 1/20 0.58
APP P05067 3/20 0.57
ESR1 P03372 1/20 0.57
ESR2 Q92731 1/20 0.57
CYP2E1 P05181 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2A6 P11509 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2B6 P20813 1/20 0.56
CYP2C19 P33261 1/20 0.56
HDAC1 Q13547 1/20 0.50
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14190035 1.00 HSD17B1 (0.62) HSD17B1HSD17B2NQO2RAB9AMEN1
SCHEMBL12562751 0.97 MEN1 (0.61) HSD17B1HSD17B2NQO2RAB9AMEN1
SCHEMBL14190049 0.97 MEN1 (0.61) HSD17B1HSD17B2NQO2RAB9AMEN1
SCHEMBL560206 0.97 MEN1 (0.61) HSD17B1HSD17B2NQO2RAB9AMEN1
SCHEMBL498650 0.97 HSD17B1 (0.65) HSD17B1HSD17B2NQO2RAB9AMEN1
SCHEMBL12562754 0.94 RAB9A (0.59) HSD17B1HSD17B2NQO2RAB9AMEN1
SCHEMBL7591626 0.94 RAB9A (0.59) HSD17B1HSD17B2NQO2RAB9AMEN1
SCHEMBL13027921 0.94 RAB9A (0.59) HSD17B1HSD17B2NQO2RAB9AMEN1
SCHEMBL13027924 0.94 RAB9A (0.59) HSD17B1HSD17B2NQO2RAB9AMEN1
SCHEMBL2129425 0.94 RAB9A (0.59) HSD17B1HSD17B2NQO2RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606304-A High-charge-density organic semiconductor molecule and preparation method and application thereof 天津大学 2023-08-18 CN claimed
CN-116606304-A High-charge-density organic semiconductor molecule and preparation method and application thereof 天津大学 2023-08-18 CN disclosed
EP-2291342-B1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KK (JP) 2014-06-04 EP disclosed
US-8377574-B2 Dibenzo[c,g]fluorene compound and an organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2013-02-19 US disclosed
US-8377574-B2 Dibenzo[c,g]fluorene compound and an organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2013-02-19 US disclosed
US-20130037843-A1 LIGHT EMITTING TRANSISTOR NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2013-02-14 US disclosed
US-20130037843-A1 LIGHT EMITTING TRANSISTOR NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2013-02-14 US disclosed
US-20110042663-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-02-24 US disclosed
US-20110042663-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-02-24 US disclosed
WO-2009139499-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-11-19 WO disclosed
US-20020114973-A1 Molecular compound, luminous material using the same, and luminous element JAPAN CHEMICAL INNOVATION INSTITUTE (JP) 2002-08-22 US disclosed
US-6355365-B1 FOR USE IN ORGANIC ELECTRO LUMINESCENCE (EL) DEVICE; EFFICIENCY JAPAN CHEMICAL INNOVATION INSTITUTE (JP) 2002-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020114973-A1 Molecular compound, luminous material using the same, and luminous element TYR, BRD4, NOTCH1 HSD17B1 4487/4885HSD17B2 4425/4885NQO2 1808/4885
US-20110042663-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME LEF1, GNG2, SCO2 HSD17B1 776/4885HSD17B2 718/4885NQO2 2566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.