SCHEMBL7587948

SCHEMBL7587948

CCCC(CCOCC)SC(C)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
THRB P10828 1/20 0.36
HDAC1 Q13547 2/20 0.31
HDAC2 Q92769 2/20 0.31
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7596283 0.82 HDAC1 (0.32) ALDH1A1TSHRHDAC1HDAC2CHRM1
SCHEMBL112653 0.81 ALDH1A1 (0.47) ALDH1A1TSHRHDAC1HDAC2CHRM1
SCHEMBL8650968 0.78 NAAA (0.44) ALDH1A1HDAC1HDAC2HDAC3HDAC4
SCHEMBL8651919 0.78 HDAC3 (0.36) ALDH1A1HDAC1HDAC2HDAC3HDAC4
SCHEMBL8650551 0.77 DGKA (0.39) ALDH1A1TSHRHDAC1HDAC2HTR2C
SCHEMBL19911082 0.74 MGAM (0.39) ALDH1A1TSHRCHRM1TDP1CYP3A4
SCHEMBL3242052 0.73 ALDH1A1 (0.52) ALDH1A1TSHRCHRM1CHRM3TDP1
SCHEMBL3242057 0.73 ALDH1A1 (0.52) ALDH1A1TSHRCHRM1CHRM3TDP1
SCHEMBL3242059 0.73 ALDH1A1 (0.52) ALDH1A1TSHRCHRM1CHRM3TDP1
Acetic Acid SCHEMBL28498892 0.72 CHRM1 (0.38) TSHRHDAC1HDAC2CHRM1AKR1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1249446-A2 Use of thio derivates as perfuming and flavoring ingredients FIRMENICH SA (CH) 2002-10-16 EP claimed