SCHEMBL7596283

SCHEMBL7596283

CCCC(CCOC)SC(C)=O

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.32
HDAC2 Q92769 2/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL584055 0.84 HDAC1 (0.37) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL7587948 0.82 ALDH1A1 (0.41) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL112653 0.82 ALDH1A1 (0.47) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL14813255 0.82 TAS1R3 (0.33) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL8651919 0.79 HDAC3 (0.36) HDAC1HDAC2HDAC3HDAC4HDAC7
SCHEMBL8650968 0.79 NAAA (0.44) HDAC1HDAC2HDAC3HDAC4HDAC7
SCHEMBL585431 0.79 POLB (0.33) HDAC1HDAC2TDP1HDAC3HDAC4
SCHEMBL585432 0.79 POLB (0.33) HDAC1HDAC2TDP1HDAC3HDAC4
SCHEMBL8650551 0.78 DGKA (0.39) HDAC1HDAC2HTR2CADRA1ATDP1
SCHEMBL584054 0.78 CTSK (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0982295-B1 Ethers; their use as perfuming or flavouring agents; their preparation FIRMENICH & CIE (CH) 2002-11-06 EP disclosed
US-6129941-A MADE BY REDUCING CIS-2-ETHYL-3-(2-METHOXYETHYL)THIIRANE TO 1-METHOXY-3-HEXANETHIOL; CONFER AN ODOR AND FLAVOR EFFECT EXTREMELY POWERFUL OF THE CLARY-SAGE TYPE; ADDING TO ENHANCE OR MODIFY THE ODOR OR FLAVOR OF A PERFUMING COMPOSITION FIRMENICH SA (CH) 2000-10-10 US disclosed
EP-0982295-A2 Ethers; their use as perfuming or flavouring agents; their preparation FIRMENICH SA (CH) 2000-03-01 EP disclosed