Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051299 | 0.82 | SELL (0.46) | RAPGEF4MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL20669678 | 0.82 | RAPGEF4 (0.33) | RAPGEF4MEN1KMT2AAR | |
| SCHEMBL24344714 | 0.78 | SMN1; SMN2 (0.46) | RAPGEF4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9935610 | 0.78 | RAPGEF4 (0.43) | RAPGEF4MEN1KMT2AALDH1A1LMNA | |
| Dimesityl Disulfide SCHEMBL896126 | 0.78 | RAPGEF4 (0.43) | RAPGEF4MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL22859266 | 0.77 | RAPGEF4 (0.32) | RAPGEF4 | |
| SCHEMBL3121456 | 0.77 | NQO2 (0.33) | — | |
| SCHEMBL2790222 | 0.77 | CYP3A4 (0.48) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL24501052 | 0.77 | RAPGEF4 (0.30) | RAPGEF4 | |
| SCHEMBL22380333 | 0.77 | SHBG (0.34) | RAPGEF4MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059472-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2023247595-A1 | PYRAZOLOPYRAZINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |
| US-20220334477-A1 | COLORED CURABLE RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-10-20 | — | — | US | disclosed |
| EP-3845531-A1 | SUBSTITUTED PYRAZOLE FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Applied Pharmaceutical Science, Inc. (CN) | 2021-07-07 | — | — | EP | disclosed |
| EP-3532477-B1 | FUSED BICYLIC PYRIDINE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-26 | — | — | EP | disclosed |
| WO-2018080917-A1 | FUSED BICYLIC PYRIDINE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |
| EP-2826783-B1 | Ruthenium and Osmium Heterocyclic Carbene Metathesis Catalysts | BERGEN TEKNOLOGIOVERFØRING AS (NO) | 2016-04-27 | — | — | EP | disclosed |
| CN-105409037-A | Process for producing active cathode material comprising mixture of metal oxide and metal sulfide and use of active cathode material in rechargeable electrochemical cells | BASF SE | 2016-03-16 | — | — | CN | disclosed |
| US-20090233142-A2 | POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20090197763-A1 | Aromatic block copolymer, decomposition method thereof and analysis method using the decomposition method | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-06 | — | — | US | disclosed |
| US-20090110995-A1 | POLYMER HAVING OXYCARBON GROUP, AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-7338740-B2 | Positive resist composition | FUJIFILM CORPORATION (JP) | 2008-03-04 | — | — | US | disclosed |
| US-7279265-B2 | Positive resist composition and pattern formation method using the same | FUJIFILM CORPORATION (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20070218335-A1 | POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF | KAO CORPORATION (JP) | 2007-09-20 | — | — | US | disclosed |
| US-7250246-B2 | Positive resist composition and pattern formation method using the same | FUJIFILM CORPORATION (JP) | 2007-07-31 | — | — | US | disclosed |
| US-7179578-B2 | Positive resist composition | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
| US-7160335-B2 | Anthraquinone dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160335-B2 | Anthraquinone dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |