Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimesityl Disulfide SCHEMBL11695386 | 0.89 | RAPGEF4 (0.36) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11316816 | 0.88 | RAPGEF4 (0.39) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11123047 | 0.88 | RAPGEF4 (0.39) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9935610 | 0.80 | RAPGEF4 (0.43) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL758797 | 0.78 | RAPGEF4 (0.41) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL24915470 | 0.75 | RAPGEF4 (0.39) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1138489 | 0.75 | CYP3A4 (0.50) | MEN1KMT2AALDH1A1GAATDP1 | |
| SCHEMBL2024568 | 0.75 | RAPGEF4 (0.39) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22368224 | 0.75 | RAPGEF4 (0.39) | RAPGEF4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21415458 | 0.75 | RAPGEF4 (0.39) | RAPGEF4MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083627-A1 | Method of Synthesis of Arylsulfur Trifluorides and Use as in situ Deoxofluorination Reagent | FLUOROTECH, LLC (US) | 2012-04-05 | — | — | US | claimed |
| CN-113039191-B | Nucleotide analogues | 奇异基因组学系统公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-110305061-B | Potential antitumor drug compound structure | 杭州新本立医药有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-110305061-A | A kind of potential antineoplastic new compound structure | 杭州新本立医药有限公司 | 2019-10-08 | — | — | CN | disclosed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| EP-2046735-B1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDES AS FLUORINATING AGENTS | UBE INDUSTRIES (JP) | 2015-05-06 | — | — | EP | disclosed |
| EP-2046735-B1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDES AS FLUORINATING AGENTS | UBE INDUSTRIES (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | UBE INDUSTRIES, LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| EP-1363959-A1 | MAKING POLYOLEFIN GRAFT COPOLYMERS WITH LOW MOLECULAR WEIGHT SIDE CHAINS USING A POLYMERIC PEROXIDE AS AN INITIATOR | Basell Poliolefine Italia S.p.A. (IT) | 2003-11-26 | — | — | EP | disclosed |
| EP-1330478-A1 | IRRADIATION PROCESS FOR MAKING OLEFIN GRAFT COPOLYMERS WITH LOW MOLECULAR WEIGHT SIDE CHAINS | Basell Poliolefine Italia S.p.A. (IT) | 2003-07-30 | — | — | EP | disclosed |
| US-6518327-B1 | Graft copolymers were made from a propylene homopolymer to which was graft polymerized polystyrene or poly(methyl methacylate) in the prsence of a hydroxylamine polymerization inhibitor | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-02-11 | — | — | US | disclosed |
| EP-1236736-A1 | 2-AMINOPURINE DERIVATIVES | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6444722-B1 | PROCESS CONTROL | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2002-09-03 | — | — | US | disclosed |
| WO-2002036649-A1 | MAKING POLYOLEFIN GRAFT COPOLYMERS WITH LOW MOLECULAR WEIGHT SIDE CHAINS USING A POLYMERIC PEROXIDE AS AN INITIATOR | BASELL TECHNOLOGY COMPANY B.V. (US) | 2002-05-10 | — | — | WO | disclosed |
| WO-2002036650-A1 | IRRADIATION PROCESS FOR MAKING OLEFIN GRAFT COPOLYMERS WITH LOW MOLECULAR WEIGHT SIDE CHAINS | BASELL TECHNOLOGY COMPANY B.V. (US) | 2002-05-10 | — | — | WO | disclosed |
| US-6057448-A | REACTION OF HALOSULFIDE WITH IMIDAZOLE TO PRODUCE SULFIDE SUBSTITUTED IMIDAZOLE | SHIONOGI & CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0949249-A1 | PROCESS FOR PRODUCING IMIDAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-4303765-A | PEPTIZATION WITH AROMATIC POLYSULFIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | PFAS, FRS2, FBL | RAPGEF4 730/4885MEN1 2875/4885KMT2A 3932/4885 |
| US-20120083627-A1 | Method of Synthesis of Arylsulfur Trifluorides and Use as in situ Deoxofluorination Reagent | AFF2, BRD2, AFF4 | RAPGEF4 3158/4885MEN1 4486/4885KMT2A 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.