Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568102 | 0.85 | PTPN2 (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7593138 | 0.84 | PTGES2 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7567353 | 0.80 | PTGES2 (0.50) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7574296 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7601861 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7588883 | 0.77 | GSK3B (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7578661 | 0.77 | CCR2 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7572367 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25140613 | 0.76 | MEN1 (0.61) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7593653 | 0.75 | ALDH1A1 (0.63) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |