Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.52 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.51 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | USP8 | P40818 | 1/20 | 0.47 |
| ▸ | IDH2 | P48735 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567283 | 0.88 | PLAU (0.62) | SLC20A2SLC20A1CCR2PLAUPLAT | |
| SCHEMBL7588412 | 0.85 | SMN1; SMN2 (0.52) | PTPN2PTPN1PTPN5ACLYALDH1A1 | |
| SCHEMBL7567292 | 0.85 | HSPD1 (0.51) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7572091 | 0.84 | CCR2 (0.54) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7567742 | 0.84 | CCR2 (0.64) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7571744 | 0.84 | HSPD1 (0.52) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7567262 | 0.83 | CCR2 (0.55) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7568150 | 0.81 | HSPD1 (0.51) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7572438 | 0.80 | SLC20A2 (0.63) | SLC20A2SLC20A1CCR2PLAUPLAT | |
| SCHEMBL7578393 | 0.80 | SLC20A2 (0.64) | SLC20A2SLC20A1CCR2PLAUPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |