Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15162504 | 0.86 | LIPG (0.46) | ADRA2AADRA2BADRA2CHTR1ATSHR | |
| SCHEMBL2141528 | 0.85 | LIPG (0.53) | TSHRPPARGPPARALIPGCYP4F2 | |
| SCHEMBL142479 | 0.84 | ADRA2B (0.44) | ADRA2AADRA2BADRA2CHTR1APPARG | |
| SCHEMBL29488434 | 0.84 | ADRA2B (0.44) | ADRA2AADRA2BADRA2CHTR1APPARG | |
| SCHEMBL8439589 | 0.84 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CHTR1ANISCH | |
| SCHEMBL11005388 | 0.83 | LIPG (0.56) | ADRA2AADRA2BADRA2CTSHRPPARG | |
| SCHEMBL11127871 | 0.83 | LIPG (0.56) | ADRA2AADRA2BADRA2CTSHRPPARG | |
| SCHEMBL15162085 | 0.83 | LIPG (0.56) | ADRA2AADRA2BADRA2CTSHRPPARG | |
| SCHEMBL30079758 | 0.82 | IDO1 (0.57) | ADRA2AADRA2BADRA2CIDO1 | |
| SCHEMBL3482048 | 0.82 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CHTR1ANISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759915-B1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS INC (US) | 2002-10-16 | — | — | EP | disclosed |
| US-5629423-A | Asymmetric synthesis of chiral secondary alcohols | CELL THERAPEUTICS, INC. (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0759915-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031450-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1995-11-23 | — | — | WO | disclosed |