Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.48 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.48 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260477 | 0.84 | PTGES2 (0.47) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL28636424 | 0.84 | KMT2A (0.65) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL398000 | 0.82 | LMNA (0.70) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL9266314 | 0.82 | PTGES2 (0.70) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL2068236 | 0.81 | ALDH1A1 (0.58) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL30737452 | 0.81 | ALDH1A1 (0.58) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL30737455 | 0.81 | PGR (0.52) | KMT2ASLC10A2SLC10A1SLC10A6POLB | |
| SCHEMBL30737349 | 0.81 | PGR (0.62) | SLC40A1 | |
| Toluene SCHEMBL27511346 | 0.80 | LMNA (0.58) | KMT2AALDH1A1MEN1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL29885455 | 0.80 | ALDH1A1 (0.56) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180675-B1 | THERAPY FOR CHEMOKINE SENSITIVE DISEASE; USING A AROMATIC (THIO)UREA COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2001-01-30 | — | — | US | disclosed |