SCHEMBL4774788

SCHEMBL4774788

C=Cc1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
ALDH1A1 P00352 2/20 0.52
ENPP2 Q13822 2/20 0.50
PTGS2 P35354 6/20 0.48
TGM2 P21980 1/20 0.48
AKR1C3 P42330 2/20 0.47
AKR1C2 P52895 1/20 0.44
AKR1C1 Q04828 1/20 0.44
MAOB P27338 1/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31189388 0.85 TDP1 (0.45) TDP1ALDH1A1ENPP2PTGS2TGM2
SCHEMBL103783 0.80 ALDH1A1 (0.58) TDP1ALDH1A1PTGS2TGM2
SCHEMBL9720721 0.80 MAOB (0.55) ALDH1A1ENPP2PTGS2AKR1C3AKR1C2
SCHEMBL177953 0.80 TDP1 (0.67) TDP1ALDH1A1
SCHEMBL9720723 0.80 MAOB (0.55) ALDH1A1ENPP2PTGS2AKR1C3AKR1C2
SCHEMBL2376239 0.79 ENPP2 (0.72) ENPP2PTGS2
SCHEMBL1202375 0.78 ENPP2 (0.52) ALDH1A1ENPP2PTGS2AKR1C3AKR1C2
SCHEMBL19276537 0.78 ALDH1A1 (0.55) TDP1ALDH1A1
SCHEMBL607349 0.78 ENPP2 (0.52) ALDH1A1ENPP2PTGS2AKR1C3AKR1C2
SCHEMBL27592527 0.78 TDP1 (0.64) TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11220062-B2 Water-dispersible thermoplastic material comprising sulfonated copolymer for use in additive manufacturing STRATASYS, INC. (US) 2022-01-11 US claimed
US-20200207025-A1 WATER-DISPERSIBLE THERMOPLASTIC MATERIAL COMPRISING SULFONATED COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS, INC. 2020-07-02 US claimed
EP-4294800-B1 APOL1 INHIBITORS AND METHODS OF USE MAZE THERAPEUTICS INC (US) 2026-05-06 EP disclosed
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 EP disclosed
CN-119730846-A Kinase modulators and methods of use thereof 神经元23公司 2025-03-28 CN disclosed
CN-119176645-B Sea water desalination method and sea water desalination system 杭州水处理技术研究开发中心有限公司 2025-03-04 CN disclosed
CN-119176645-A Sea water desalination method and sea water desalination system 杭州水处理技术研究开发中心有限公司 2024-12-24 CN disclosed
WO-2024249252-A1 METHODS OF USING APOL1 INHIBITORS MAZE THERAPEUTICS, INC. (US) 2024-12-05 WO disclosed
US-20240316038-A1 APOL1 INHIBITORS AND METHODS OF USE HERCULES CAPITAL, INC., AS AGENT 2024-09-26 US disclosed
WO-2023244788-A9 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2024-09-12 WO disclosed
US-20240191087-A1 WATER DISPERSIBLE SULFONATED THERMOPLASTIC COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS INC (US) 2024-06-13 US disclosed
US-20040204421-A1 Certain 1,3-disubstituted isoquinoline derivatives EISAI CO., LTD. 2004-10-14 US disclosed
US-6790844-B2 MUSCLE RELAXANTS; ANTISEROTONINE AGENT EISAI CO., LTD (JP) 2004-09-14 US disclosed
US-20020013460-A1 Condensed pyridine compound EISAI CO., LTD 2002-01-31 US disclosed
US-6340759-B1 ANTISPASMODIC AGENTS EISAI CO., LTD. (JP) 2002-01-22 US disclosed
EP-1020445-A1 FUSED PYRIDINE DERIVATIVES Eisai Co., Ltd. (JP) 2000-07-19 EP disclosed
EP-0570932-B1 Styrenic block copolymer and process for producing same IDEMITSU KOSAN CO (JP) 1997-07-23 EP disclosed
US-5418290-A Compatability with other resins, adhesion IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5391626-A Syndiotactic, high performance, compatibility and adhesiveness; molding materials IDEMITSU KOSAN CO., LTD. (JP) 1995-02-21 US disclosed
EP-0570932-A2 Styrenic block copolymer and process for producing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013460-A1 Condensed pyridine compound MUSK, HTR1A, PAX3 TDP1 1197/4885ALDH1A1 2989/4885ENPP2 4029/4885
US-20040204421-A1 Certain 1,3-disubstituted isoquinoline derivatives MUSK, HTR1A, RYR1 TDP1 326/4885ALDH1A1 1071/4885ENPP2 4088/4885
US-20240316038-A1 APOL1 INHIBITORS AND METHODS OF USE APOL1, SAAL1, APOB TDP1 760/4885ALDH1A1 1839/4885ENPP2 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.