Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28121988 | 0.78 | PRKDC (0.46) | PRKDCATRALDH1A1SMN1; SMN2 | |
| SCHEMBL12891205 | 0.77 | TDP1 (0.55) | TDP1TAS1R3TAS1R1ALDH1A1HTR2A | |
| SCHEMBL7589008 | 0.77 | TDP1 (0.55) | TDP1TAS1R3TAS1R1ALDH1A1HTR2A | |
| SCHEMBL7207685 | 0.75 | MMP13 (0.51) | GAAMMP2MMP9 | |
| SCHEMBL13101213 | 0.74 | TDP1 (0.52) | TDP1TAS1R3TAS1R1PSEN1PSEN2 | |
| SCHEMBL13112963 | 0.73 | TDP1 (0.52) | TDP1TAS1R3TAS1R1ALDH1A1HTR2A | |
| SCHEMBL24791574 | 0.72 | TDP1 (0.53) | TDP1TAS1R3TAS1R1PSEN1PSEN2 | |
| SCHEMBL29175748 | 0.71 | TDP1 (0.62) | TDP1 | |
| SCHEMBL3107979 | 0.70 | CA2 (0.58) | TDP1ALDH1A1KCNH2POLBGAA | |
| SCHEMBL5203081 | 0.70 | ALDH1A1 (0.42) | TDP1TAS1R3TAS1R1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949540-B1 | Method for producing lithographic printing plate suitable for laser scan exposure, and photopolymerizable composition | FUJIFILM CORP (JP) | 2012-05-02 | — | — | EP | disclosed |