Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954849 | 0.90 | POLB (0.51) | ALDH1A1CYP2C19MEN1KMT2ATSHR | |
| SCHEMBL7946411 | 0.88 | CYP2C19 (0.48) | ALDH1A1CYP2C19MEN1KMT2ATSHR | |
| SCHEMBL7954837 | 0.88 | CYP2C19 (0.65) | ALDH1A1CYP2C19MEN1KMT2ATSHR | |
| SCHEMBL13468059 | 0.83 | TP53 (0.55) | ALDH1A1MEN1KMT2ATSHRFKBP1A | |
| SCHEMBL7852753 | 0.82 | TDP1 (0.49) | ALDH1A1TSHRHCRTR2SMN1; SMN2 | |
| SCHEMBL13469108 | 0.81 | KDM4E (0.54) | ALDH1A1MEN1KMT2ATSHRFKBP1A | |
| SCHEMBL20366865 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ATSHRFKBP1A | |
| SCHEMBL15614467 | 0.80 | MEN1 (0.52) | ALDH1A1MEN1KMT2ATSHRFKBP1A | |
| SCHEMBL2157261 | 0.79 | GAA (0.64) | ALDH1A1MEN1KMT2AFKBP1AKDM4E | |
| SCHEMBL2157294 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ATSHRFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006380-A1 | Pyrrole derivatives, their preparation and pharmaceutical compositions containing them | MIGNANI SERGE (FR) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006380-A1 | Pyrrole derivatives, their preparation and pharmaceutical compositions containing them | TNF, IL2, ZC3HAV1 | ALDH1A1 1762/4885CYP2C19 405/4885MEN1 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.