Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | FKBP1A | P62942 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.48 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946476 | 0.86 | ALDH1A1 (0.56) | GAAFKBP1AALDH1A1KDM4EMEN1 | |
| SCHEMBL3456792 | 0.86 | ALDH1A1 (0.58) | FKBP1AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7585371 | 0.84 | ALDH1A1 (0.65) | GAAFKBP1AALDH1A1KDM4EMEN1 | |
| SCHEMBL2226633 | 0.83 | MMP2 (0.52) | GAAALDH1A1KMT2A | |
| SCHEMBL10860840 | 0.83 | GAA (0.59) | GAAFKBP1AALDH1A1KDM4EMEN1 | |
| SCHEMBL10947045 | 0.82 | GAA (0.58) | GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL2157294 | 0.82 | ALDH1A1 (0.47) | GAAFKBP1AALDH1A1KDM4EMTOR | |
| SCHEMBL7592715 | 0.82 | ALDH1A1 (0.61) | FKBP1AALDH1A1 | |
| SCHEMBL21715104 | 0.82 | ALDH1A1 (0.63) | FKBP1AALDH1A1MEN1KMT2A | |
| SCHEMBL13468136 | 0.81 | ALDH1A1 (0.60) | FKBP1AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361253-A1 | COMPOUNDS | Selcia Limited (GB) | 2011-08-31 | — | — | EP | disclosed |
| US-20110184011-A1 | Compounds | SELCIA LIMITED (GB) | 2011-07-28 | — | — | US | disclosed |
| WO-2010029364-A1 | COMPOUNDS | SELCIA LIMITED (GB) | 2010-03-18 | — | — | WO | disclosed |
| US-20020006380-A1 | Pyrrole derivatives, their preparation and pharmaceutical compositions containing them | MIGNANI SERGE (FR) | 2002-01-17 | — | — | US | disclosed |
| US-6194426-B1 | CONTROLLING TUMOR NECROSIS FACTOR | RHONA-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |
| US-4584297-A | Pyrrolo[1,2-c]-1,3-thiazines | RHONE-POULENC SANTE (FR) | 1986-04-22 | — | — | US | disclosed |
| US-4546100-A | Pyrrolo[1,2-c]thiazoles useful as antithrombotic agents | RHONE-POULENC SANTE (FR) | 1985-10-08 | — | — | US | disclosed |
| US-4539400-A | Pyridin-3-yl substituted ortho-fused pyrrole derivatives | RHONE-POULENC SANTE (FR) | 1985-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184011-A1 | Compounds | COL1A1, ALDH1A2, COL2A1 | GAA 3174/4885FKBP1A 1140/4885ALDH1A1 74/4885 |
| US-20020006380-A1 | Pyrrole derivatives, their preparation and pharmaceutical compositions containing them | TNF, IL2, ZC3HAV1 | GAA 3684/4885FKBP1A 530/4885ALDH1A1 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.