Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 10/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.41 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13468059 | 0.84 | TP53 (0.55) | ALDH1A1FKBP1AMEN1KMT2ATSHR | |
| SCHEMBL7946476 | 0.83 | ALDH1A1 (0.56) | ALDH1A1FKBP1AMEN1KMT2AGAA | |
| SCHEMBL2157190 | 0.82 | CA12 (0.44) | GAAGALR3NR2F2RAB9A | |
| SCHEMBL2157261 | 0.82 | GAA (0.64) | ALDH1A1FKBP1AMEN1KMT2AGAA | |
| SCHEMBL20366865 | 0.81 | ALDH1A1 (0.56) | ALDH1A1FKBP1AMEN1KMT2ATSHR | |
| SCHEMBL7954849 | 0.80 | POLB (0.51) | ALDH1A1FKBP1AMEN1KMT2ATSHR | |
| SCHEMBL7589095 | 0.79 | ALDH1A1 (0.52) | ALDH1A1FKBP1AMEN1KMT2ATSHR | |
| SCHEMBL4038706 | 0.78 | GPR119 (0.46) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL7954837 | 0.78 | CYP2C19 (0.65) | ALDH1A1FKBP1AMEN1KMT2ATSHR | |
| SCHEMBL7946411 | 0.78 | CYP2C19 (0.48) | ALDH1A1FKBP1AMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361253-A1 | COMPOUNDS | Selcia Limited (GB) | 2011-08-31 | — | — | EP | disclosed |
| US-20110184011-A1 | Compounds | SELCIA LIMITED (GB) | 2011-07-28 | — | — | US | disclosed |
| WO-2010029364-A1 | COMPOUNDS | SELCIA LIMITED (GB) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184011-A1 | Compounds | COL1A1, ALDH1A2, COL2A1 | ALDH1A1 74/4885FKBP1A 1140/4885MEN1 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.