SCHEMBL758911

SCHEMBL758911

COc1ccccc1CC(=O)c1ccccc1-c1ccccc1OC

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.61
GAA P10253 1/20 0.52
ATM Q13315 1/20 0.52
HPGD P15428 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
HIF1A Q16665 1/20 0.49
CNR2 P34972 1/20 0.49
TSHR P16473 2/20 0.49
MAPT P10636 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
RCE1 Q9Y256 1/20 0.47
NPC1 O15118 1/20 0.46
CTSD P07339 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332837 0.88 TTR (0.66) TTRATMHPGDL3MBTL1HIF1A
SCHEMBL5045736 0.83 NPC1 (0.49) HPGDL3MBTL1MEN1KMT2ALMNA
SCHEMBL7505195 0.78 HDAC8 (0.52) HPGDKMT2ALMNASMN1; SMN2KDM4E
SCHEMBL236891 0.78 TTR (0.70) TTRGAAATML3MBTL1HIF1A
SCHEMBL597834 0.78 L3MBTL1 (0.69) TTRL3MBTL1HIF1ATSHRMAPT
SCHEMBL536179 0.78 HTT (0.62) HPGDTSHRKMT2AKDM4EALDH1A1
SCHEMBL1957953 0.78 SMN1; SMN2 (0.56) HPGDL3MBTL1MAPTKMT2ALMNA
SCHEMBL16324582 0.77 TTR (0.60) TTRGAAHPGDL3MBTL1HIF1A
SCHEMBL7499747 0.77 HDAC8 (0.55) HPGDKMT2ALMNASMN1; SMN2NPC1
SCHEMBL1246697 0.77 RAB9A (0.65) TTRGAAHPGDL3MBTL1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415631-B Liquid crystal composition, mixture, polymer/liquid crystal composite material, optical element and use thereof 捷恩智株式会社 2022-10-14 CN disclosed
CN-107406407-B Liquid crystal composition, polymer/liquid crystal composite material, optical element, and compound 捷恩智株式会社 2021-01-22 CN disclosed
CN-111918951-A Liquid crystal composition, monomer/liquid crystal mixture, polymer/liquid crystal composite material, liquid crystal element and chiral compound 捷恩智株式会社 2020-11-10 CN disclosed
CN-111718727-A Liquid crystal composition, mixture, polymer/liquid crystal composite material, optical switching element, and laser radar 捷恩智株式会社 2020-09-29 CN disclosed
US-20200299581-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL SWITCHING DEVICE USING SAME JNC CORPORATION (JP) 2020-09-24 US disclosed
US-10633589-B2 Liquid crystal medium, optical device and liquid crystal compound JNC CORPORATION (JP) 2020-04-28 US disclosed
CN-110577836-A Liquid crystal composition for light conversion element, mixture, polymer/liquid crystal composite material, element, and laser radar 捷恩智株式会社 2019-12-17 CN disclosed
EP-2774968-B1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORP (JP) 2019-11-20 EP disclosed
WO-2019198422-A1 LIQUID CRYSTAL COMPOSITION, MONOMER/(LIQUID CRYSTAL) MIXTURE, POLYMER/(LIQUID CRYSTAL) COMPOSITE MATERIAL, LIQUID CRYSTAL ELEMENT, AND CHIRAL COMPOUND JNC株式会社 2019-10-17 WO disclosed
US-20190316036-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORPORATION (JP) 2019-10-17 US disclosed
US-7648647-B2 Polymer/liquid crystal composite and liquid crystal element KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2010-01-19 US disclosed
EP-2098583-A2 Optically isotropic liquid crystal medium and optical device Chisso Corporation (JP) 2009-09-09 EP disclosed
US-20090135368-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE CHISSO CORPORATION (JP) 2009-05-28 US disclosed
US-20090051855-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE CHISSO CORPORATION (JP) 2009-02-26 US disclosed
EP-2028253-A1 Optically isotropic liquid crystal medium and optical device Chisso Corporation (JP) 2009-02-25 EP disclosed
US-20080280071-A1 POLYMER/LIQUID CRYSTAL COMPOSITE AND LIQUID CRYSTAL ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2008-11-13 US disclosed
EP-0348063-B1 THERMOPLASTIC ELASTOMER AND PHOTOSENSITIVE RESIN COMPOSITION BASED THEREON, AND PRINTING PLATE PRECURSOR COMPRISING THE COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1993-05-26 EP disclosed
US-5177171-A SULFONIC ACID GROUP-CONTAINING POLYURETHANE AND A PHOTOSENSITIVE RESIN COMPOSITION CONTAINING THE SAME ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-01-05 US disclosed
US-5053316-A THERMOPLASTIC ELASTOMER AND PHOTOSENSITIVE RESIN COMPOSITION BASED THEREON, AND PRINTING PLATE PRECURSOR COMPRISING THE COMPOSITION ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1991-10-01 US disclosed
EP-0348063-A1 Thermoplastic elastomer and photosensitive resin composition based thereon, and printing plate precursor comprising the composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1989-12-27 EP disclosed