Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 3/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592910 | 0.83 | PDE4A (0.36) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL25074982 | 0.80 | EGFR (0.44) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL30249078 | 0.80 | EGFR (0.44) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL29735301 | 0.79 | SLC22A12 (0.37) | SLC22A12PDE4APDE4CPDE4DEPAS1 | |
| SCHEMBL23087503 | 0.79 | SLC22A12 (0.37) | SLC22A12PDE4APDE4CPDE4DEPAS1 | |
| SCHEMBL6603224 | 0.77 | ALPL (0.35) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL31661008 | 0.76 | DYRK1A (0.40) | ALDH1A1KDM4EMAPTHPGDPDE9A | |
| SCHEMBL17287531 | 0.76 | ADORA2A (0.36) | ALDH1A1KDM4EMAPTPDE4APDE4C | |
| SCHEMBL3627292 | 0.75 | EPAS1 (0.38) | SLC22A12PDE4APDE4CPDE4DVEGFA | |
| SCHEMBL31350672 | 0.74 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTKMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |
| EP-1238016-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | Gentian AS (NO) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042368-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | GENTIAN AS (NO) | 2001-06-14 | — | — | WO | disclosed |