Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | EP300 | Q09472 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15145878 | 0.87 | MEN1 (0.52) | MEN1KMT2ATDP1EP300CA1 | |
| SCHEMBL3081594 | 0.87 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1L3MBTL1USP2 | |
| SCHEMBL22252403 | 0.86 | KEAP1 (0.69) | MEN1KMT2AEP300 | |
| SCHEMBL27826958 | 0.84 | MCOLN3 (0.72) | MEN1KMT2ATDP1EP300CA1 | |
| SCHEMBL22345889 | 0.84 | ALDH1A1 (0.68) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3783869 | 0.84 | CA1 (0.74) | CA1CA2 | |
| SCHEMBL2835167 | 0.83 | POLB (0.66) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL15770989 | 0.83 | KMT2A (0.68) | MEN1KMT2ATDP1EP300ALDH1A1 | |
| SCHEMBL28261753 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2ATDP1EP300CA2 | |
| SCHEMBL2067538 | 0.82 | ALDH1A1 (0.68) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |