SCHEMBL7589660

SCHEMBL7589660

Cc1ccc2c(C)c(C(=O)O)ccc2c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 3/20 0.42
LDHB P07195 3/20 0.42
MCL1 Q07820 2/20 0.40
HAAO P46952 1/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP1A2 P05177 2/20 0.38
GRM1 Q13255 1/20 0.38
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NOTUM Q6P988 1/20 0.36
PTGER4 P35408 1/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C9 P11712 2/20 0.36
TSHR P16473 1/20 0.36
PDE10A Q9Y233 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 1/20 0.36
ALB P02768 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015552 0.85 CYP1A2 (0.50) HAAOALDH1A1CYP1A2GRM1KDM4E
SCHEMBL10015553 0.85 LDHA (0.47) LDHALDHBMCL1ALDH1A1CYP1A2
SCHEMBL195882 0.84 CYP1A2 (0.44) LDHALDHBMCL1HAAOALDH1A1
SCHEMBL9408349 0.82 HAAO (0.42) LDHALDHBMCL1HAAOALDH1A1
SCHEMBL9249101 0.82 HAAO (0.42) LDHALDHBMCL1HAAOALDH1A1
Water SCHEMBL27552128 0.82 HAAO (0.42) LDHALDHBMCL1HAAOALDH1A1
Ammonia Solution, Strong SCHEMBL28622226 0.82 HAAO (0.42) LDHALDHBMCL1HAAOALDH1A1
SCHEMBL9558286 0.79 NR4A1 (0.50) MCL1ALDH1A1KDM4EHPGDHSD17B10
Cyclohexane SCHEMBL9558619 0.78 HAAO (0.40) LDHALDHBMCL1HAAOALDH1A1
SCHEMBL605144 0.77 CYP1A2 (0.46) MCL1HAAOALDH1A1CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0988342-B1 PROCESS FOR CRYSTALLIZING BLENDS OF POLYETHYLENE TEREPHTHALATE AND POLYETHYLENE ISOPHTHALATE M & G POLIMERI ITALIA SPA (IT) 2002-10-23 EP disclosed
US-5919872-A Process for crystallizing blends of polyethylene terephthalate and polyethylene isophthalate SHELL OIL COMPANY (US) 1999-07-06 US disclosed
EP-0105824-B1 POLYISOPHTHALATES AND COPOLYMERS THEREOF HAVING HIGH BARRIER PROPERTIES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-04-27 EP disclosed
US-4643925-A PACKAGING FOODS AND BEVERAGES, CANS AND BOTTLES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-02-17 US disclosed
EP-0105016-B1 POLYISOPHTHALATE AND COPOLYMERS THEREOF HAVING REDUCED CYCLIC DIMER CONTENT, AND A PROCESS FOR MAKING THE SAME THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-01-21 EP disclosed
EP-0103531-B1 POLYETHYLENE ISOPHTHALATE HAVING REDUCED CYCLIC DIMER CONTENT AND PROCESS THEREFOR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-12-30 EP disclosed
US-4604257-A POLYESTERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-08-05 US disclosed
US-4482586-A Multi-layer polyisophthalate and polyterephthalate articles and process therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-11-13 US disclosed
US-4447595-A HAZE-FREE PACKAGING MATERIALS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-05-08 US disclosed
EP-0105824-A1 Polyisophthalates and copolymers thereof having high barrier properties THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-04-18 EP disclosed
EP-0105825-A2 Multi-layer polyisophthalate and polyterephthalate articles and process therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-04-18 EP disclosed
EP-0105016-A1 Polyisophthalate and copolymers thereof having reduced cyclic dimer content, and a process for making the same THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-04-04 EP disclosed
EP-0103531-A1 Polyethylene isophthalate having reduced cyclic dimer content and process therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-03-21 EP disclosed
EP-0102913-A2 Polyterephthalates having high clarity and process for making same THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-03-14 EP disclosed
US-4424337-A Polyisophthalate and copolymers thereof having reduced cyclic dimer content, and a process for making the same THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-01-03 US disclosed
US-4418188-A PROTONIC ACID CATALYSTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-29 US disclosed
US-4403090-A Polyisophthalates and copolymers thereof having high barrier properties THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-09-06 US disclosed