SCHEMBL10015552

SCHEMBL10015552

Cc1c(C(=O)O)ccc2c(C)c(C(=O)O)ccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
GRM1 Q13255 1/20 0.46
TSHR P16473 1/20 0.44
ALDH1A1 P00352 3/20 0.43
ALOX15 P16050 1/20 0.43
HAAO P46952 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
GABRA4 P48169 1/20 0.43
GABRE P78334 1/20 0.43
GABRA6 Q16445 1/20 0.43
GABRG1 Q8N1C3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14640813 0.89 GRM1 (0.51) CYP1A2GRM1TSHRALDH1A1CSNK2A1
SCHEMBL31389208 0.86 CYP1A2 (0.58) CYP1A2GRM1TSHRALDH1A1ALOX15
SCHEMBL128319 0.86 CYP1A2 (0.58) CYP1A2GRM1TSHRALDH1A1ALOX15
SCHEMBL30218700 0.85 KDM4E (0.50) CYP1A2TSHRALDH1A1KDM4EHPGD
SCHEMBL18936303 0.85 KDM4E (0.50) CYP1A2TSHRALDH1A1KDM4EHPGD
SCHEMBL7589660 0.85 LDHA (0.42) CYP1A2GRM1TSHRALDH1A1HAAO
Ammonia Solution, Strong SCHEMBL29137499 0.83 CYP1A2 (0.55) CYP1A2GRM1TSHRALDH1A1ALOX15
SCHEMBL19138866 0.82 CFD (0.54) CYP1A2TSHRALDH1A1KDM4EHPGD
SCHEMBL23909581 0.81 KMT2A (0.47) CYP1A2TSHRALDH1A1ALOX15KDM4E
SCHEMBL23909590 0.81 TSHR (0.44) CYP1A2TSHRALDH1A1ALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026097688-A1 METAL-ORGANIC FRAMEWORK MATERIAL, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国石油天然气股份有限公司 2026-05-15 WO disclosed
US-20150333263-A1 POLYMER COMPRISING A NAPHTHALENE GROUP AND ITS USE IN ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-19 US disclosed
US-8373005-B2 Process for the synthesis of ethers of aromatic acids E I DU PONT DE NEMOURS AND COMPANY (US) 2013-02-12 US disclosed
US-8207374-B2 Process for the synthesis of ethers of aromatic acids E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-26 US disclosed
US-7985825-B2 Process for the synthesis of ethers of aromatic acids E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-26 US disclosed
US-7943723-B2 Process for the synthesis of ethers of aromatic acids E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-17 US disclosed
US-20110060118-A1 PROCESS FOR THE SYNTHESIS OF FLUORINATED ETHERS OF AROMATIC ACIDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 US disclosed
US-20100105860-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E. I DU PONT DE NEMOURS AND COMPANY (US) 2010-04-29 US disclosed
US-20100048856-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-25 US disclosed
US-20100016540-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-01-21 US disclosed
US-20080182961-A1 PROCESS FOR THE SYNTHESIS OF HYDROXY AROMATIC ACIDS RITTER JOACHIM C 2008-07-31 US disclosed
US-20080182962-A1 PROCESS FOR THE SYNTHESIS OF HYDROXY AROMATIC ACIDS RITTER JOACHIM C 2008-07-31 US disclosed
US-20080167441-A1 Forming a salt from a halogenated aromatic acid with a base in water; adding copper source with an amine ligand, forming an n-hydroxy aromatic acid; and alkylating to form n-alkoxy aromatic acid RITTER JOACHIM C 2008-07-10 US disclosed
US-20080139843-A1 PROCESS FOR THE SYNTHESIS OF HYDROXY AROMATIC ACIDS RITTER JOACHIM C 2008-06-12 US disclosed
US-20080125604-A1 PROCESS FOR THE SYNTHESIS OF HYDROXY AROMATIC ACIDS E. I. DU PONT DE NEMOURS AND COMPANY 2008-05-29 US disclosed
US-7378547-B1 Process for the synthesis of hydroxy aromatic acids E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-05-27 US disclosed
US-7358391-B1 Process for the synthesis of hydroxy aromatic acids E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-15 US disclosed
US-7351856-B1 Process for the synthesis of hydroxy aromatic acids E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-01 US disclosed
US-7335791-B1 Process for the synthesis of hydroxy aromatic acids E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-02-26 US disclosed
US-3991038-A Polyamide polymer of alkyladamantane diamine and cyclic hydrocarbon diacid SUN VENTURES, INC. (US) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048856-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS TYR, DDC, AHR CYP1A2 60/4885GRM1 1462/4885TSHR 296/4885
US-20080182961-A1 PROCESS FOR THE SYNTHESIS OF HYDROXY AROMATIC ACIDS PAH, TYR, AHR CYP1A2 48/4885GRM1 3482/4885TSHR 581/4885
US-20080167441-A1 Forming a salt from a halogenated aromatic acid with a base in water; adding copper source with an amine ligand, forming an n-hydroxy aromatic acid; and alkylating to form n-alkoxy aromatic acid AHR, ALK, PAH CYP1A2 315/4885GRM1 3117/4885TSHR 711/4885
US-20100016540-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS DDC, TYR, AHR CYP1A2 71/4885GRM1 3210/4885TSHR 1990/4885
US-20110060118-A1 PROCESS FOR THE SYNTHESIS OF FLUORINATED ETHERS OF AROMATIC ACIDS EWSR1, ALK, TYR CYP1A2 1037/4885GRM1 2993/4885TSHR 70/4885
US-20080182962-A1 PROCESS FOR THE SYNTHESIS OF HYDROXY AROMATIC ACIDS PAH, TYR, AHR CYP1A2 48/4885GRM1 3482/4885TSHR 581/4885
US-20100105860-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS DDC, TYR, AOC1 CYP1A2 30/4885GRM1 2262/4885TSHR 511/4885
US-20080139843-A1 PROCESS FOR THE SYNTHESIS OF HYDROXY AROMATIC ACIDS PAH, TYR, AHR CYP1A2 48/4885GRM1 3482/4885TSHR 581/4885
US-20080125604-A1 PROCESS FOR THE SYNTHESIS OF HYDROXY AROMATIC ACIDS PAH, TYR, AHR CYP1A2 48/4885GRM1 3482/4885TSHR 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.