Flupyrsulfuron

Flupyrsulfuron

SCHEMBL7589707

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2nc(C(F)(F)F)ccc2C(=O)O)n1.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
TTR P02766 2/20 0.45
KMT2A Q03164 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALB P02768 1/20 0.45
THRB P10828 1/20 0.45
GAA P10253 1/20 0.41
PPOX P50336 1/20 0.36
CDK1 P06493 1/20 0.35
TBXA2R P21731 4/20 0.35
ALDH3A1 P30838 1/20 0.33
TP53 P04637 1/20 0.33
GLA P06280 1/20 0.33
MAPT P10636 1/20 0.33
HPSE Q9Y251 1/20 0.33
FBP1 P09467 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33
AKR1B10 O60218 1/20 0.33
AKR1B1 P15121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flupyrsulfuron SCHEMBL7578529 0.89 KMT2A (0.35) MEN1TTRKMT2ATDP1ALB
Flazasulfuron SCHEMBL7586436 0.86 MEN1 (0.45) MEN1TTRKMT2ATDP1ALB
Aclonifen SCHEMBL7596875 0.84 MEN1 (0.51) MEN1TTRKMT2ATDP1ALB
Flupyrsulfuron SCHEMBL7581127 0.83 TDP1 (0.59) MEN1TTRKMT2ATDP1GAA
Nicosulfuron SCHEMBL7579393 0.83 MEN1 (0.44) MEN1TTRKMT2ATDP1ALB
Aclonifen SCHEMBL7588805 0.83 TDP1 (0.45) MEN1TTRKMT2ATDP1ALB
Flupyrsulfuron SCHEMBL7580925 0.82 TDP1 (0.55) MEN1TTRKMT2ATDP1GAA
Halosulfuron SCHEMBL7584262 0.81 MEN1 (0.46) MEN1TTRKMT2ATDP1ALB
Flupyrsulfuron SCHEMBL7578681 0.81 MEN1 (0.49) MEN1TTRKMT2ATDP1GAA
Flupyrsulfuron SCHEMBL115535 0.81 GAA (0.61) MEN1KMT2AGAACDK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885TTR 1945/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.