Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dcmu SCHEMBL7588041 | 0.93 | APEX1 (0.47) | HRASKMT2AMEN1APEX1MAPT | |
| Fluometuron SCHEMBL7582543 | 0.89 | TP53 (0.53) | KMT2AMEN1MAPTTP53GABRP | |
| Isoproturon SCHEMBL7584700 | 0.88 | BACE1 (0.39) | HRASCYP1A2CYP3A4CYP2C19MAPT | |
| Dimefuron SCHEMBL7586926 | 0.83 | KMT2A (0.63) | HRASKMT2AMEN1APEX1MAPT | |
| Propanil SCHEMBL7587518 | 0.81 | CYP3A4 (0.47) | HRASCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL39558 | 0.80 | ALDH1A1 (0.48) | CYP3A4ALDH1A1GABRPGABRDGABRA1 | |
| Phenmedipham SCHEMBL7580294 | 0.74 | ALDH1A1 (0.49) | CYP3A4KMT2AMEN1MAPTALDH1A1 | |
| Mecoprop SCHEMBL7581550 | 0.74 | TSHR (0.48) | KMT2AMEN1MAPTGABRPGABRD | |
| SCHEMBL10388804 | 0.74 | CYP3A4 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C19MAPT | |
| Clopyralid SCHEMBL7586160 | 0.73 | GABRA2 (0.42) | CYP3A4CYP2C19KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020004457-A1 | Herbicidal composition | SYNGENTA PARTICIPATIONS AG (CH) | 2002-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004457-A1 | Herbicidal composition | PPOX, ALAD, DDT | HRAS 4381/4885CYP1A2 47/4885CYP3A4 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.