Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 5/20 | 0.46 |
| ▸ | MMP8 | P22894 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021705 | 1.00 | MMP3 (0.46) | MMP3MMP8MMP9ALDH1A1MMP1 | |
| SCHEMBL542708 | 0.96 | ALDH1A1 (0.47) | MMP3MMP8MMP9ALDH1A1MMP1 | |
| SCHEMBL20581478 | 0.90 | ALDH1A1 (0.50) | ALDH1A1HTTSMN1; SMN2CYP2C19TSHR | |
| SCHEMBL20581479 | 0.90 | ALDH1A1 (0.50) | ALDH1A1HTTSMN1; SMN2CYP2C19TSHR | |
| SCHEMBL6682726 | 0.80 | NAAA (0.50) | ALDH1A1SMN1; SMN2NAAACYP2C19TSHR | |
| SCHEMBL14501881 | 0.80 | ALDH1A1 (0.53) | MMP9ALDH1A1TSHR | |
| SCHEMBL27745864 | 0.80 | L3MBTL1 (0.43) | MMP3MMP8MMP9ALDH1A1MMP1 | |
| SCHEMBL6263485 | 0.79 | MMP3 (0.48) | MMP3MMP8MMP9MMP1L3MBTL1 | |
| SCHEMBL8879002 | 0.79 | MMP3 (0.49) | MMP3MMP8MMP9MMP1L3MBTL1 | |
| SCHEMBL15515610 | 0.79 | L3MBTL1 (0.49) | MMP3MMP8MMP9MMP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759915-B1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS INC (US) | 2002-10-16 | — | — | EP | disclosed |
| WO-1999033468-A9 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS INC (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999033468-A1 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS, INC. (US) | 1999-07-08 | — | — | WO | disclosed |
| US-5629423-A | Asymmetric synthesis of chiral secondary alcohols | CELL THERAPEUTICS, INC. (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0759915-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031450-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1995-11-23 | — | — | WO | disclosed |