Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.64 |
| ▸ | CCR9 | P51686 | 6/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | S100A9 | P06702 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589382 | 0.86 | FFAR4 (0.71) | FFAR4CCR9ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7594352 | 0.82 | HSD17B2 (0.52) | CCR9ALDH1A1LMNAGAAHTT | |
| SCHEMBL12407078 | 0.81 | FFAR4 (0.55) | FFAR4CCR9LMNAGAATP53 | |
| SCHEMBL29087421 | 0.80 | KMT2A (0.64) | FFAR4CCR9FBP1GAA | |
| SCHEMBL7569763 | 0.79 | FFAR4 (0.59) | FFAR4CCR9FBP1GAA | |
| SCHEMBL7590053 | 0.79 | FFAR4 (0.59) | FFAR4CCR9FBP1GAATP53 | |
| SCHEMBL7577285 | 0.78 | FFAR4 (0.59) | FFAR4CCR9ALDH1A1LMNAGAA | |
| SCHEMBL9930848 | 0.78 | CCR2 (0.71) | — | |
| SCHEMBL7588981 | 0.77 | ALDH1A1 (0.64) | FFAR4ALDH1A1LMNAGAAHTT | |
| SCHEMBL7595506 | 0.77 | FFAR4 (0.57) | FFAR4CCR9FBP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |