Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | CCR9 | P51686 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589492 | 0.90 | PTGES2 (0.56) | HSD17B2MEN1KMT2APTGES2ALDH1A1 | |
| SCHEMBL7594610 | 0.85 | CCR2 (0.65) | HSD17B2MCL1MEN1KMT2ACCR2 | |
| SCHEMBL7591561 | 0.82 | FFAR4 (0.64) | ALDH1A1LMNAGAAHTTCCR9 | |
| SCHEMBL9931199 | 0.81 | CCR2 (0.57) | MEN1KMT2ACCR2ALDH1A1LMNA | |
| SCHEMBL7588981 | 0.80 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL17340514 | 0.80 | HSD17B2 (0.75) | HSD17B2MCL1MEN1KMT2ACCR2 | |
| SCHEMBL7593595 | 0.79 | CCR9 (0.62) | HSD17B2MCL1CCR2PTGES2KDM1A | |
| SCHEMBL7589760 | 0.79 | CCR2 (0.59) | MEN1KMT2ACCR2PTGES2ALDH1A1 | |
| SCHEMBL15228509 | 0.79 | MCL1 (0.70) | MCL1MEN1KMT2ATDP1CCR2 | |
| SCHEMBL12406982 | 0.79 | PTGES2 (0.56) | MCL1MEN1KMT2ATDP1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |