SCHEMBL7591862

SCHEMBL7591862

Cc1ccc(OP(=O)(O)O)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 11/20 0.48
INPP5A Q14642 6/20 0.48
AKT1 P31749 1/20 0.48
INPP5B P32019 2/20 0.48
MRGPRX4 Q96LA9 1/20 0.41
ACHE P22303 1/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
RAB9A P51151 1/20 0.41
ATM Q13315 1/20 0.41
KDM4E B2RXH2 1/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14274128 0.81 INPPL1 (0.52) INPPL1INPP5AAKT1INPP5BMRGPRX4
SCHEMBL14403284 0.81 ACHE (0.61) INPPL1INPP5AAKT1INPP5BACHE
SCHEMBL8620844 0.81 INPPL1 (0.52) INPPL1INPP5AAKT1INPP5BCYP2C9
SCHEMBL109597 0.81 INPPL1 (0.52) INPPL1INPP5AAKT1INPP5BPOLB
SCHEMBL4372630 0.81 INPPL1 (0.52) INPPL1INPP5AAKT1INPP5BMAPT
SCHEMBL6928304 0.79 INPPL1 (0.50) INPPL1INPP5AAKT1INPP5BKDM4E
SCHEMBL28656347 0.79 INPPL1 (0.50) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL27559347 0.79 INPPL1 (0.50) INPPL1INPP5AAKT1INPP5BPOLB
SCHEMBL31406716 0.78 INPPL1 (0.48) INPPL1INPP5AAKT1INPP5BALDH1A1
SCHEMBL11360950 0.78 INPPL1 (0.48) INPPL1INPP5AAKT1INPP5BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5403503-A Containing a mixture of polyoxyalkylene glycol, polyester, phosphate and(or) phosphite IDEMITSU KOSAN CO., LTD. (JP) 1995-04-04 US claimed
EP-0739973-B1 Refrigerating machine oil composition IDEMITSU KOSAN CO (JP) 2002-10-16 EP disclosed
EP-0507158-B1 Refrigerating machine oil composition IDEMITSU KOSAN CO (JP) 1997-08-20 EP disclosed
EP-0739973-A1 Refrigerating machine oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-10-30 EP disclosed
EP-0461262-B1 Use of refrigerator oil composition for Hydrofluorcarbon refrigerant IDEMITSU KOSAN CO (JP) 1995-05-03 EP disclosed
US-5403503-A Containing a mixture of polyoxyalkylene glycol, polyester, phosphate and(or) phosphite IDEMITSU KOSAN CO., LTD. (JP) 1995-04-04 US disclosed
US-5310492-A Wear resistance, lubricant oil and metal carboxylate IDEMITSU KOSAN CO., LTD. (JP) 1994-05-10 US disclosed
EP-0507158-A1 Refrigerating machine oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-10-07 EP disclosed
EP-0461262-A1 Use of refrigerator oil composition for Hydrofluorcarbon refrigerant IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-12-18 EP disclosed