Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | INPPL1 | O15357 | 5/20 | 0.52 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | INPP5B | P32019 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL8941755 | 0.91 | ACHE (0.50) | ACHEINPPL1INPP5AALDH1A1CYP3A4 | |
| SCHEMBL7591862 | 0.81 | INPPL1 (0.48) | ACHEINPPL1INPP5AAKT1INPP5B | |
| SCHEMBL8620844 | 0.81 | INPPL1 (0.52) | INPPL1INPP5AAKT1INPP5BCYP2C9 | |
| SCHEMBL109597 | 0.81 | INPPL1 (0.52) | INPPL1INPP5AAKT1INPP5BHPGD | |
| SCHEMBL20107983 | 0.80 | INPPL1 (0.50) | INPPL1INPP5AAKT1INPP5BALDH1A1 | |
| SCHEMBL27559347 | 0.79 | INPPL1 (0.50) | INPPL1INPP5AAKT1INPP5BHPGD | |
| SCHEMBL28656347 | 0.79 | INPPL1 (0.50) | INPPL1INPP5AAKT1INPP5BTDP1 | |
| SCHEMBL14274128 | 0.78 | INPPL1 (0.52) | INPPL1INPP5AAKT1INPP5BALDH1A1 | |
| SCHEMBL31406716 | 0.78 | INPPL1 (0.48) | INPPL1INPP5AAKT1INPP5BALDH1A1 | |
| SCHEMBL11360950 | 0.78 | INPPL1 (0.48) | INPPL1INPP5AAKT1INPP5BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151024-A1 | STING AGONISTIC COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-05-18 | — | — | US | disclosed |
| EP-4134134-A1 | STING AGONISTIC COMPOUND | ONO Pharmaceutical Co., Ltd. (JP) | 2023-02-15 | — | — | EP | disclosed |
| EP-4134098-A1 | METHOD OF CANCER THERAPY | ONO Pharmaceutical Co., Ltd. (JP) | 2023-02-15 | — | — | EP | disclosed |
| US-20070248692-A1 | COMBINATION THERAPY USING PENTAFLUOROBENZENESULFONAMIDES AND ANTINEOPLASTIC AGENTS | AMGEN INC. (US) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248692-A1 | COMBINATION THERAPY USING PENTAFLUOROBENZENESULFONAMIDES AND ANTINEOPLASTIC AGENTS | ETV6, FANCF, FANCI | ACHE 4594/4885INPPL1 2472/4885INPP5A 3362/4885 |
| US-20230151024-A1 | STING AGONISTIC COMPOUND | STING1, CGAS, TLR1 | ACHE 819/4885INPPL1 284/4885INPP5A 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.