Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.31 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridan SCHEMBL7594988 | 0.89 | HDAC3 (0.32) | FFAR1TSHR | |
| SCHEMBL7787061 | 0.78 | MAPT (0.37) | HTTSMN1; SMN2FFAR1MAPTTSHR | |
| SCHEMBL7797026 | 0.78 | HDAC4 (0.38) | NPC1RAB9ASMN1; SMN2GRK6MAPT | |
| SCHEMBL7592240 | 0.74 | MAPT (0.41) | SLC6A2SLC6A4SLC6A3POLBAKR1C3 | |
| SCHEMBL8877458 | 0.74 | KDM4E (0.35) | HTTSMN1; SMN2MAPTTSHR | |
| SCHEMBL7591680 | 0.73 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3POLBNPC1 | |
| SCHEMBL7797048 | 0.71 | HDAC4 (0.39) | HTTMAPT | |
| SCHEMBL7787075 | 0.71 | MAPT (0.39) | BRD4SMN1; SMN2MAPTTSHR | |
| SCHEMBL7592395 | 0.71 | TAS1R3 (0.34) | SLC6A2SLC6A4SLC6A3POLBNPC1 | |
| Acridan SCHEMBL6586926 | 0.70 | ALDH1A1 (0.32) | BRD4SMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778946-B1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN INC (US) | 2002-10-23 | — | — | EP | claimed |
| EP-0778946-B1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN INC (US) | 2002-10-23 | — | — | EP | disclosed |