Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.48 |
| ▸ | CTSL | P07711 | 8/20 | 0.46 |
| ▸ | CTSK | P43235 | 9/20 | 0.41 |
| ▸ | CTSB | P07858 | 6/20 | 0.41 |
| ▸ | CTSH | P09668 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523059 | 0.90 | CTSS (0.53) | CTSSCTSLCTSKCTSBCTSH | |
| SCHEMBL5523879 | 0.86 | CTSS (0.66) | CTSSCTSLCTSKCTSBCTSH | |
| SCHEMBL5523065 | 0.86 | CTSS (0.49) | CTSSCTSLCTSKCTSBCTSH | |
| SCHEMBL5517692 | 0.86 | CTSS (0.49) | CTSSCTSLCTSKCTSBCTSH | |
| SCHEMBL5532245 | 0.81 | CTSS (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5526860 | 0.79 | CTSK (0.50) | CTSSCTSLCTSKCTSBCTSH | |
| SCHEMBL7591245 | 0.77 | ALDH1A1 (0.48) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5529190 | 0.77 | CTSL (0.48) | CTSSCTSLCTSKCTSBCTSH | |
| SCHEMBL5528340 | 0.77 | CTSL (0.48) | CTSSCTSLCTSKCTSBCTSH | |
| SCHEMBL5523001 | 0.77 | CTSK (0.51) | CTSSCTSLCTSKCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178958-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000055125-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |