SCHEMBL7592892

SCHEMBL7592892

N=C(N)NCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31541507 0.94 KISS1R (0.56) KISS1R
SCHEMBL30464843 0.93 MC4R (0.55) KISS1R
SCHEMBL29968155 0.93 CCKBR (0.55) KISS1R
SCHEMBL29533726 0.93 CCKBR (0.55) KISS1R
SCHEMBL30919247 0.93 OPRD1 (0.57) KISS1R
SCHEMBL8021033 0.91 KISS1R (0.60) KISS1R
SCHEMBL29784960 0.91 MC4R (0.52) KISS1R
SCHEMBL29419497 0.90 CCKBR (0.55) KISS1R
SCHEMBL30451792 0.90 NPBWR1 (0.52) KISS1R
SCHEMBL28295885 0.90 MC4R (0.55) KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0438600-B2 ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF SHISEIDO CO LTD (JP) 2002-10-09 — — EP disclosed
US-6156555-A Method of preparing an enzyme participating in C-terminal amidation SHISEIDO COMPANY LTD. (JP) 2000-12-05 — — US disclosed
EP-0666318-B1 Enzyme participating in c-terminal amidation, and method of preparing same and use thereof SHISEIDO CO LTD (JP) 2000-11-29 — — EP disclosed
US-5871995-A Purified enzymes participating in C-terminal amidation SHISEIDO COMPANY, LTD. (JP) 1999-02-16 — — US disclosed
EP-0884389-A1 Enzyme participating in C-terminal amidation, and method of preparing same and use thereof SHISEIDO COMPANY LIMITED (JP) 1998-12-16 — — EP disclosed
EP-0438600-B1 ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF SHISEIDO CO LTD (JP) 1996-02-07 — — EP disclosed
EP-0666318-A1 Enzyme participating in c-terminal amidation, and method of preparing same and use thereof SHISEIDO COMPANY LIMITED (JP) 1995-08-09 — — EP disclosed
US-5354675-A Amidation of glycine SHISEIDO COMPANY LTD. (JP) 1994-10-11 — — US disclosed
EP-0447547-B1 C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE SHISEIDO CO LTD (JP) 1994-07-27 — — EP disclosed
EP-0447547-A1 C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE SHISEIDO COMPANY LIMITED (JP) 1991-09-25 — — EP disclosed
EP-0438600-A1 ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF SHISEIDO COMPANY LIMITED (JP) 1991-07-31 — — EP disclosed
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