Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 8/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645210 | 0.86 | UBE2M (0.39) | UBE2MDCUN1D1ALDH1A1TP53TRPA1 | |
| SCHEMBL7569363 | 0.82 | P2RX1 (0.44) | TP53MAPTTACR1 | |
| SCHEMBL6811870 | 0.81 | TLR8 (0.48) | UBE2MDCUN1D1ALDH1A1TP53TRPA1 | |
| SCHEMBL7868222 | 0.81 | KDR (0.41) | UBE2MDCUN1D1TP53TACR1 | |
| SCHEMBL7593142 | 0.79 | MYC (0.42) | ALDH1A1MAPTCYP1A2 | |
| SCHEMBL7569407 | 0.77 | P2RY14 (0.37) | UBE2MDCUN1D1ALDH1A1TP53TRPA1 | |
| SCHEMBL7075937 | 0.72 | ALDH1A1 (0.43) | UBE2MDCUN1D1ALDH1A1TRPA1MME | |
| SCHEMBL6819508 | 0.72 | TLR8 (0.50) | ALDH1A1TP53TRPA1MAPTCYP1A2 | |
| SCHEMBL7719609 | 0.70 | CCR2 (0.40) | TACR1 | |
| SCHEMBL7645182 | 0.69 | ALDH1A1 (0.44) | ALDH1A1TRPA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144399-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144399-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000034261-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |