Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.50 |
| ▸ | CHRNG | P07510 | 2/20 | 0.50 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.50 |
| ▸ | CHRND | Q07001 | 2/20 | 0.50 |
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654796 | 1.00 | LMNA (0.69) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| SCHEMBL13855542 | 0.99 | LMNA (0.71) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| SCHEMBL17532634 | 0.93 | LMNA (0.79) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| SCHEMBL26815273 | 0.92 | LMNA (0.69) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| SCHEMBL615296 | 0.89 | HTT (0.72) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| Hydrochloric Acid SCHEMBL616935 | 0.87 | HTT (0.70) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| SCHEMBL335088 | 0.87 | HTT (0.70) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| SCHEMBL7682044 | 0.86 | LMNA (0.69) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| SCHEMBL14288941 | 0.86 | LMNA (0.69) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| SCHEMBL14288938 | 0.86 | LMNA (0.69) | LMNASMN1; SMN2HTTTGM2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138361-B2 | C-10 carbamates of taxanes | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090306014-A1 | C-10 CARBAMATES OF TAXANES | ACIDOPHIL LLC (US) | 2009-12-10 | — | — | US | disclosed |
| WO-2005035003-A9 | COMPOSITIONS AND METHODS FOR INCREASING DRUG EFFICIENCY | DIHEDRON CORP (US) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306014-A1 | C-10 CARBAMATES OF TAXANES | CASP10, S100A10, ATXN10 | LMNA 602/4885SMN1; SMN2 144/4885HTT 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.