SCHEMBL7594502

SCHEMBL7594502

Cc1cc(Cl)c(OP(=O)(O)O)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SRC P12931 3/20 0.56
INPPL1 O15357 10/20 0.45
INPP5A Q14642 6/20 0.44
AKT1 P31749 1/20 0.43
INPP5B P32019 2/20 0.43
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 3/20 0.37
PGK1 P00558 2/20 0.36
PGK2 P07205 2/20 0.36
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25259132 0.83 INPPL1 (0.48) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL9347214 0.79 INPPL1 (0.45) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL4821203 0.79 ALDH1A1 (0.42) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL5074713 0.78 SRC (0.66) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL29768788 0.78 ALDH1A1 (0.42) SRCALDH1A1CYP3A4TSHRMAPK1
SCHEMBL7591862 0.75 INPPL1 (0.48) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL25222316 0.74 INPPL1 (0.59) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL7631008 0.73 ALDH1A1 (0.52) INPPL1INPP5AAKT1INPP5BALDH1A1
SCHEMBL9417149 0.72 ALDH1A1 (0.41) SRCINPPL1INPP5AALDH1A1KDM4E
SCHEMBL8480850 0.72 SRC (0.53) SRCINPPL1INPP5AAKT1INPP5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5403503-A Containing a mixture of polyoxyalkylene glycol, polyester, phosphate and(or) phosphite IDEMITSU KOSAN CO., LTD. (JP) 1995-04-04 US claimed
EP-0739973-B1 Refrigerating machine oil composition IDEMITSU KOSAN CO (JP) 2002-10-16 EP disclosed
EP-0507158-B1 Refrigerating machine oil composition IDEMITSU KOSAN CO (JP) 1997-08-20 EP disclosed
EP-0739973-A1 Refrigerating machine oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-10-30 EP disclosed
EP-0461262-B1 Use of refrigerator oil composition for Hydrofluorcarbon refrigerant IDEMITSU KOSAN CO (JP) 1995-05-03 EP disclosed
US-5403503-A Containing a mixture of polyoxyalkylene glycol, polyester, phosphate and(or) phosphite IDEMITSU KOSAN CO., LTD. (JP) 1995-04-04 US disclosed
US-5310492-A Wear resistance, lubricant oil and metal carboxylate IDEMITSU KOSAN CO., LTD. (JP) 1994-05-10 US disclosed
EP-0507158-A1 Refrigerating machine oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-10-07 EP disclosed
EP-0461262-A1 Use of refrigerator oil composition for Hydrofluorcarbon refrigerant IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-12-18 EP disclosed