Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594203 | 0.96 | PARP1 (0.45) | PARP1PDE10AHPGDSL3MBTL1LMNA | |
| SCHEMBL7597610 | 0.81 | PARP1 (0.43) | PARP1PDE10AHPGDSL3MBTL1LMNA | |
| Bromide SCHEMBL7460540 | 0.80 | PARP1 (0.42) | PARP1PDE10AHPGDSL3MBTL1LMNA | |
| Jineol Acetate SCHEMBL8608939 | 0.77 | ALDH1A1 (0.51) | PDE10AHPGDSL3MBTL1LMNAKDM4E | |
| SCHEMBL7466188 | 0.77 | PARP1 (0.56) | PARP1PDE10AHPGDSL3MBTL1LMNA | |
| SCHEMBL27444535 | 0.76 | PDE10A (0.43) | PARP1PDE10AHPGDSL3MBTL1LMNA | |
| SCHEMBL21044049 | 0.72 | PDE10A (0.52) | PARP1PDE10AL3MBTL1LMNAKDM4E | |
| SCHEMBL250301 | 0.70 | LMNA (0.65) | L3MBTL1LMNAUSP2KDM4EPOLB | |
| SCHEMBL28012242 | 0.70 | KDM4E (0.44) | PDE10AHPGDSL3MBTL1LMNAUSP2 | |
| SCHEMBL8611942 | 0.69 | HPGDS (0.58) | PARP1PDE10AHPGDSL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747362-B1 | Substituted quinoline herbicide intermediates and process | BASF AG (DE) | 2002-10-30 | — | — | EP | disclosed |
| US-5633380-A | DEHALOGENATED, DESALTED HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0747362-A1 | Substituted quinoline herbicide intermediates and process | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | disclosed |