SCHEMBL75947

SCHEMBL75947

COC(=O)c1cc2c(-c3ccccc3)c3ccccc3c(-c3ccccc3)c2cc1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NR4A2 P43354 5/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
GAA P10253 1/20 0.46
MAPK8 P45983 2/20 0.45
LMNA P02545 2/20 0.44
AXL P30530 1/20 0.44
CREBBP Q92793 1/20 0.43
PLA2G2A P14555 1/20 0.43
PTPN1 P18031 1/20 0.43
FABP3 P05413 1/20 0.43
FABP4 P15090 1/20 0.43
FABP5 Q01469 1/20 0.43
GABRA1 P14867 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28391493 0.78 SMN1; SMN2 (0.60) SMN1; SMN2ALDH1A1HPGDNR4A2MEN1
SCHEMBL6170807 0.78 LMNA (0.50) SMN1; SMN2KDM4EALDH1A1HPGDNPSR1
SCHEMBL12873537 0.78 SLC6A3 (0.61) SMN1; SMN2KDM4EALDH1A1HPGDNPSR1
SCHEMBL29094948 0.77 FABP4 (0.54) SMN1; SMN2KDM4EALDH1A1HPGDNPSR1
SCHEMBL2512793 0.76 KDM4E (0.62) KDM4EALDH1A1HPGDNPSR1MEN1
SCHEMBL29438042 0.76 KDM4E (0.62) KDM4EALDH1A1HPGDNPSR1MEN1
SCHEMBL30478408 0.76 LMNA (0.49) SMN1; SMN2KDM4EALDH1A1HPGDNPSR1
SCHEMBL9898507 0.76 NR4A2 (0.50) SMN1; SMN2KDM4EALDH1A1HPGDNPSR1
SCHEMBL27552364 0.76 NR4A2 (0.56) SMN1; SMN2KDM4EALDH1A1HPGDNR4A2
SCHEMBL337450 0.75 CA12 (0.47) KDM4EALDH1A1HPGDMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642215-B2 Chemically-resistant shelter coatings LOMBARDI JOHN 2010-01-05 US claimed
US-20080153690-A1 CHEMICALLY-RESISTANT SHELTER COATINGS LOMBARDI JOHN L 2008-06-26 US claimed
US-7259122-B1 Chemically-resistant shelter coating LOMBARDI JOHN 2007-08-21 US claimed
US-8298976-B2 Pathogen-resistant fabrics LOMBARDI JOHN L (US) 2012-10-30 US disclosed
WO-2012135541-A1 PATHOGEN-RESISTANT FABRICS LOMBARDI JOHN L (US) 2012-10-04 WO disclosed
US-8216969-B2 Pathogen-resistant fabrics LOMBARDI JOHN L (US) 2012-07-10 US disclosed
US-8129303-B2 Pathogen-resistant fabrics LOMBARDI JOHN L (US) 2012-03-06 US disclosed
US-8114810-B2 Pathogen-resistant fabrics LOMBARDI JOHN L (US) 2012-02-14 US disclosed
US-8058206-B2 Pathogen-resistant fabrics U.S. GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY 2011-11-15 US disclosed
US-8058207-B2 Pathogen-resistant fabrics LOMBARDI JOHN L (US) 2011-11-15 US disclosed
US-20110250424-A1 Pathogen-Resistant Fabrics LOMBARDI JOHN L 2011-10-13 US disclosed
US-20110184164-A1 Pathogen-Resistant Fabrics U.S. GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY 2011-07-28 US disclosed
US-20110183569-A1 Pathogen-Resistant Fabrics LOMBARDI JOHN L 2011-07-28 US disclosed
US-20110183571-A1 Pathogen-Resistant Fabrics LOMBARDI JOHN L 2011-07-28 US disclosed
US-7915197-B2 Photocatalyst capable of generating singlet oxygen from ambient air in polymeric material; protection from toxic chemical and biological agents (\"CBAs\"); emergency medical or military use such as body bags, protective clothing, shelters LOMBARDI JOHN L 2011-03-29 US disclosed
US-7642215-B2 Chemically-resistant shelter coatings LOMBARDI JOHN 2010-01-05 US disclosed
WO-2009035833-A2 PATHOGEN-RESISTANT COATINGS LOMBARDI JOHN L (US) 2009-03-19 WO disclosed
US-20080171803-A1 Pathogen-resistant coatings LOMBARDI JOHN L 2008-07-17 US disclosed
US-20080153690-A1 CHEMICALLY-RESISTANT SHELTER COATINGS LOMBARDI JOHN L 2008-06-26 US disclosed
US-7259122-B1 Chemically-resistant shelter coating LOMBARDI JOHN 2007-08-21 US disclosed