Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599024 | 1.00 | CA1 (0.42) | CA1CA2ACHEATMCNR1 | |
| SCHEMBL7601629 | 0.94 | FOLH1 (0.40) | FOLH1ALDH1A1CYP3A4TSHRKMT2A | |
| SCHEMBL7597936 | 0.94 | FOLH1 (0.40) | FOLH1ALDH1A1CYP3A4TSHRKMT2A | |
| SCHEMBL7600882 | 0.93 | TRPM8 (0.41) | CA1CA2ACHEHDAC1HDAC6 | |
| SCHEMBL7600478 | 0.93 | FOLH1 (0.38) | CNR1CNR2CTSLCTSSCTSK | |
| SCHEMBL7597915 | 0.93 | FOLH1 (0.38) | CNR1CNR2CTSLCTSSCTSK | |
| SCHEMBL7596771 | 0.92 | CA1 (0.38) | CA1CA2ACHEATMCNR1 | |
| SCHEMBL7600372 | 0.91 | CA1 (0.39) | CA1CA2ACHEATMCNR1 | |
| SCHEMBL7600355 | 0.90 | CA1 (0.45) | CA1CA2ACHEATMCNR1 | |
| SCHEMBL7597929 | 0.90 | CA1 (0.45) | CA1CA2ACHEATMCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |