Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601084 | 0.94 | FOLH1 (0.37) | FOLH1SIRT2 | |
| SCHEMBL7597349 | 0.94 | FOLH1 (0.37) | FOLH1SIRT2 | |
| SCHEMBL7599024 | 0.92 | CA1 (0.42) | CA1CA2ACHEATMCNR1 | |
| SCHEMBL7595006 | 0.92 | CA1 (0.42) | CA1CA2ACHEATMCNR1 | |
| SCHEMBL7595801 | 0.90 | FOLH1 (0.43) | CA1CA2ACHEATMCNR1 | |
| SCHEMBL7600358 | 0.90 | FOLH1 (0.43) | CA1CA2ACHEATMCNR1 | |
| SCHEMBL7600372 | 0.89 | CA1 (0.39) | CA1CA2ACHEATMCNR1 | |
| SCHEMBL7601629 | 0.86 | FOLH1 (0.40) | FOLH1SIRT2ALDH1A1 | |
| SCHEMBL7597936 | 0.86 | FOLH1 (0.40) | FOLH1SIRT2ALDH1A1 | |
| SCHEMBL7600882 | 0.85 | TRPM8 (0.41) | CA1CA2ACHEHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |