Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 8/20 | 0.41 |
| ▸ | MMP9 | P14780 | 6/20 | 0.41 |
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | MMP7 | P09237 | 3/20 | 0.41 |
| ▸ | MMP14 | P50281 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593717 | 0.94 | ELANE (0.44) | ELANEMMP1MMP9MMP3MMP2 | |
| SCHEMBL7591572 | 0.90 | ELANE (0.47) | ELANEMMP1MMP9MMP3MMP2 | |
| SCHEMBL7397719 | 0.85 | ELANE (0.44) | ELANEMMP1MMP9MMP3MMP2 | |
| SCHEMBL7403302 | 0.83 | MMP1 (0.48) | ELANEMMP1MMP9MMP3MMP2 | |
| SCHEMBL7402161 | 0.83 | MMP3 (0.48) | ELANEMMP1MMP9MMP3MMP2 | |
| SCHEMBL7397759 | 0.82 | MMP3 (0.49) | ELANEMMP1MMP9MMP3MMP2 | |
| SCHEMBL8508599 | 0.82 | MMP3 (0.42) | ELANEMMP1MMP9MMP3MMP2 | |
| SCHEMBL7367575 | 0.81 | ANPEP (0.46) | MMP1MMP9MMP3MMP2MMP7 | |
| SCHEMBL8511173 | 0.81 | MMP3 (0.42) | ELANEMMP1MMP9MMP3MMP2 | |
| SCHEMBL7589246 | 0.78 | MMP1 (0.40) | MMP1MMP9MMP3MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826000-B1 | PEPTIDE COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION AND THEIR THERAPEUTIC USES | DARWIN DISCOVERY LTD (GB) | 2002-10-23 | — | — | EP | disclosed |