Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.48 |
| ▸ | MMP3 | P08254 | 7/20 | 0.48 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | MMP7 | P09237 | 3/20 | 0.48 |
| ▸ | MMP14 | P50281 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402161 | 0.97 | MMP3 (0.48) | MMP1MMP3MMP2MMP9MMP7 | |
| SCHEMBL7397759 | 0.96 | MMP3 (0.49) | MMP1MMP3MMP2MMP9MMP7 | |
| SCHEMBL7397719 | 0.95 | ELANE (0.44) | MMP1MMP3MMP2MMP9MMP7 | |
| SCHEMBL7403845 | 0.86 | HPGD (0.43) | MMP1MMP3MMP2MMP9MMP7 | |
| SCHEMBL7593717 | 0.85 | ELANE (0.44) | MMP1MMP3MMP2MMP9MMP7 | |
| SCHEMBL7595170 | 0.83 | ELANE (0.46) | MMP1MMP3MMP2MMP9MMP7 | |
| SCHEMBL8510054 | 0.83 | ANPEP (0.43) | MMP1MMP3MMP2MMP9MMP7 | |
| SCHEMBL8508599 | 0.82 | MMP3 (0.42) | MMP1MMP3MMP2MMP9MMP7 | |
| SCHEMBL8764880 | 0.82 | ANPEP (0.42) | MMP1MMP3MMP2MMP9MMP7 | |
| SCHEMBL7403732 | 0.82 | LTA4H (0.42) | MMP1MMP3MMP2MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996035711-A1 | PEPTIDE COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION, AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-14 | — | — | WO | claimed |
| WO-1996035711-A1 | PEPTIDE COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION, AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-14 | — | — | WO | disclosed |