Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593762 | 0.96 | CA2 (0.41) | CA2ALDH1A1HSD17B10LMNAMEN1 | |
| SCHEMBL6227052 | 0.86 | LMNA (0.37) | CA2ALDH1A1LMNACHRM1TBXA2R | |
| SCHEMBL7595235 | 0.85 | CA2 (0.47) | CA2ALDH1A1HSD17B10LMNAMEN1 | |
| SCHEMBL7594746 | 0.85 | CA2 (0.34) | CA2ALDH1A1 | |
| SCHEMBL7588474 | 0.81 | LMNA (0.34) | CA2ALDH1A1LMNA | |
| SCHEMBL7595517 | 0.81 | ALDH1A1 (0.39) | CA2ALDH1A1HSD17B10LMNACHRM1 | |
| SCHEMBL7588477 | 0.80 | CA2 (0.31) | CA2 | |
| SCHEMBL7589252 | 0.79 | CA2 (0.31) | CA2 | |
| SCHEMBL7592499 | 0.79 | CA2 (0.31) | CA2 | |
| SCHEMBL7591103 | 0.78 | MMP13 (0.33) | CA2ALDH1A1HSD17B10LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| WO-2000037115-A1 | WATER-SOLUBLE CONTRAST MEDIA FOR X-RAY IMAGING | NYCOMED IMAGING AS (NO) | 2000-06-29 | — | — | WO | disclosed |