Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 17/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.63 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.44 |
| ▸ | ITGB8 | P26012 | 6/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592559 | 1.00 | ITGAV (0.63) | ITGAVITGB3ITGB6ITGB8ITGA5 | |
| SCHEMBL7553084 | 1.00 | ITGAV (0.63) | ITGAVITGB3ITGB6ITGB8ITGA5 | |
| SCHEMBL7595601 | 0.87 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB8ITGA5 | |
| SCHEMBL7591574 | 0.87 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB8ITGA5 | |
| SCHEMBL7187503 | 0.87 | ITGAV (0.48) | ITGAVITGB3ITGB6ITGB8ITGA5 | |
| SCHEMBL7554194 | 0.86 | ITGAV (0.47) | ITGAVITGB3ITGB6ITGB8ITGA5 | |
| SCHEMBL7557728 | 0.86 | ITGAV (0.47) | ITGAVITGB3ITGB6ITGB8ITGA5 | |
| SCHEMBL4374753 | 0.85 | ITGB3 (0.65) | ITGAVITGB3ITGB6ITGB1ITGA2B | |
| SCHEMBL7592528 | 0.85 | ITGAV (0.48) | ITGAVITGB3ITGB6ITGB8ITGA5 | |
| SCHEMBL7595883 | 0.85 | ITGAV (0.48) | ITGAVITGB3ITGB6ITGB8ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013318-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013318-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGS1, PTGIS, PTGS2 | ITGAV 3210/4885ITGB3 2956/4885ITGB6 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.